The bus between La Crosse and St. Louis takes 16h 50m. The bus runs, on average, 4 times per week from La Crosse to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a week between La Crosse and St. Louis. The service departs La Crosse at 2:30 PM in the afternoon, which arrives into St. Louis at 06:20:00. All services require a transfer at Milwaukee and take an average of 16h 50m. The schedules shown below are for the next available departures.
Want to know about travelling from La Crosse to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from La Crosse to St. Louis. However, there are services departing from La Crosse station and arriving at St Louis Bus Station via Milwaukee station and Chicago Bus Station. The journey, including transfers, takes approximately 16h 50m.
La Crosse to St. Louis bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to St. Louis bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
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The distance between La Crosse and St. Louis is 581.9 km. The road distance is 664 km.
You can take a bus from La Crosse to St Louis Bus Station via Milwaukee, Milwaukee Intermodal Station, and Chicago Bus Station in around 13h 20m.
