The average bus between La Jolla and Irvine takes 4h 4m and the fastest bus takes 3h 30m. The bus service runs several times per day from La Jolla to Irvine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between La Jolla and Irvine. The earliest departure is at 7:29 AM in the morning, and the last departure from La Jolla is at 9:30 PM which arrives into Irvine at 1:00 AM. All services require a transfer at Old Town Transit Center and take an average of 4h 4m. The schedules shown below are for the next available departures.


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3h 41m • 2 changesWant to know about travelling from La Jolla to Irvine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from La Jolla to Irvine. However, there are services departing from La Jolla station and arriving at Irvine station via Anaheim Regional Transportation Intermodal Center. The journey, including transfers, takes approximately 4h 4m.
La Jolla to Irvine bus services, operated by San Diego Metro Transit, depart from San Diego station.
La Jolla to Irvine bus services, operated by San Diego Metro Transit, arrive at Main-Harvard station.
Book your La Jolla to Irvine bus tickets online with San Diego Metro Transit, Flixbus USA and 2 other operators.
The distance between La Jolla and Irvine is 104.7 km. The road distance is 183 km.
You can take a bus from Silverado St & Herschel Av to Main-Harvard via Old Town Transit Center, San Diego, Anaheim Regional Transportation Intermodal Center, and Artic - Dock 4 in around 4h 49m.