The average bus between La Jolla and San Ysidro takes 2h 20m and the fastest bus takes 1h 28m. The bus service runs several times per day from La Jolla to San Ysidro. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between La Jolla and San Ysidro. The earliest departure is at 10:48 AM in the morning, and the last departure from La Jolla is at 11:00 PM which arrives into San Ysidro at 3:56 AM. All services require a transfer at Old Town Transit Center and take an average of 2h 20m. The schedules shown below are for the next available departures.


1h 53m • 2 changes

2h 9m • 2 changes

1h 54m • 2 changes

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1h 53m • 2 changes

2h 9m • 2 changes

1h 54m • 2 changes

1h 54m • 2 changes

1h 32m • 2 changes

1h 43m • 2 changes

1h 28m • 2 changes

1h 41m • 2 changes

1h 32m • 2 changes

1h 43m • 2 changes

1h 28m • 2 changes

1h 41m • 2 changes

1h 32m • 2 changes

1h 43m • 2 changes

1h 28m • 2 changes

1h 41m • 2 changes

1h 32m • 2 changes

1h 43m • 2 changes

1h 28m • 2 changes

1h 41m • 2 changesWant to know about travelling from La Jolla to San Ysidro? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from La Jolla to San Ysidro. However, there are services departing from Silverado St & Herschel Av station and arriving at San Ysidro Bus Terminal station via Old Town Transit Center station. The journey, including transfers, takes approximately 2h 20m.
La Jolla to San Ysidro bus services, operated by San Diego Metro Transit, depart from Silverado St & Herschel Av station.
La Jolla to San Ysidro bus services, operated by Greyhound USA, arrive at San Ysidro Bus Terminal station.
The distance between La Jolla and San Ysidro is 39.3 km. The road distance is 45 km.
You can take a bus from Silverado St & Herschel Av to San Ysidro Bl & I-805 via Old Town Transit Center, San Diego Greyhound Bus Stop, and San Ysidro Transit Center in around 2h 4m.