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La Mesa to Anaheim buses

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Trip Overview

The average bus between La Mesa and Anaheim takes 3h 14m and the fastest bus takes 2h 23m. The bus service runs several times per day from La Mesa to Anaheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 14m
Duration
100 mi
Distance
$23
Average price
3 times a day
Frequency

Line 10 bus, bus

best
  1. Take the bus from University Av & College Av to Old Town Transit Centerbus bus 10
  2. Take the bus from San Diego to Anaheim Regional Transportation Intermodal Centerbus bus FlixBus N2003 / ...
3h 27m
$16–29

La Mesa to Anaheim bus times

Buses run 3 times a day between La Mesa and Anaheim. The earliest departure is at 7:30 AM in the morning, and the last departure from La Mesa is at 10:19 PM which arrives into Anaheim at 10:15 AM. All services require a transfer at Old Town Transit Center and take an average of 3h 14m. The schedules shown below are for the next available departures.

Departing Friday, October 16, 2026

  •  → 

    San Diego Metro TransitFlixbus USA3h 27m • 1 change

  •  → 

    San Diego Metro TransitGreyhound USA3h 6m • 1 change

  •  → 

    Arrives next day

    San Diego Metro TransitFlixbus USA2h 23m • 1 change

  •  → 

    Arrives next day

    San Diego Metro TransitFlixbus USA11h 56m • 1 change

Departing Monday, October 19, 2026

  •  → 

    San Diego Metro TransitFlixbus USA2h 45m • 1 change

  •  → 

    San Diego Metro TransitGreyhound USA2h 42m • 1 change

  •  → 

    San Diego Metro TransitFlixbus USA3h 27m • 1 change

  •  → 

    San Diego Metro TransitGreyhound USA3h 6m • 1 change
  • Show more

Departing Tuesday, October 20, 2026

  •  → 

    San Diego Metro TransitGreyhound USA2h 42m • 1 change

  •  → 

    San Diego Metro TransitFlixbus USA3h 27m • 1 change

  •  → 

    San Diego Metro TransitGreyhound USA3h 6m • 1 change

  •  → 

    Arrives next day

    San Diego Metro TransitFlixbus USA2h 23m • 1 change

Departing Wednesday, October 21, 2026

  •  → 

    San Diego Metro TransitFlixbus USA2h 45m • 1 change

  •  → 

    San Diego Metro TransitGreyhound USA2h 42m • 1 change

  •  → 

    San Diego Metro TransitGreyhound USA3h 6m • 1 change

  •  → 

    Arrives next day

    San Diego Metro TransitFlixbus USA2h 23m • 1 change

Departing Thursday, October 22, 2026

  •  → 

    San Diego Metro TransitFlixbus USA2h 45m • 1 change

  •  → 

    San Diego Metro TransitGreyhound USA2h 42m • 1 change

  •  → 

    San Diego Metro TransitFlixbus USA3h 27m • 1 change

Frequently asked questions

Want to know about travelling from La Mesa to Anaheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from La Mesa to Anaheim.ExpandLaunch map view
  • Distance: 100.4 mi
  • Duration: 3h 14m

What companies run services between La Mesa, CA, USA and Anaheim, CA, USA?

You can take a bus from University Av & College Av to Anaheim Regional Transportation Intermodal Center via Old Town Transit Center and San Diego in around 3h 27m.

Operators