The average bus between La Mesa and Fresno takes 10h 15m and the fastest bus takes 9h 38m. The bus service runs several times per day from La Mesa to Fresno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between La Mesa and Fresno. The earliest departure is at 4:36 AM at night, and the last departure from La Mesa is at 10:19 PM which arrives into Fresno at 2:20 PM. All services require a transfer at Old Town Transit Center and take an average of 10h 15m. The schedules shown below are for the next available departures.
Want to know about travelling from La Mesa to Fresno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from La Mesa to Fresno. However, there are services departing from La Mesa station and arriving at Fresno station via Fresno Bus Station station. The journey, including transfers, takes approximately 10h 15m.
La Mesa to Fresno bus services, operated by San Diego Metro Transit, depart from San Diego station.
La Mesa to Fresno bus services, operated by San Diego Metro Transit, arrive at Fresno Bus Station.
The distance between La Mesa and Fresno is 508.8 km. The road distance is 574 km.
Flixbus USA operates a bus from San Diego to Fresno Bus Station once daily. Tickets cost $50–80 and the journey takes 8h 30m. Greyhound USA also services this route once daily.