The average bus between La Mesa and Irvine takes 4h 23m and the fastest bus takes 3h 13m. The bus service runs several times per day from La Mesa to Irvine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between La Mesa and Irvine. The earliest departure is at 7:30 AM in the morning, and the last departure from La Mesa is at 10:19 PM which arrives into Irvine at 11:39 AM. All services require a transfer at Old Town Transit Center and take an average of 4h 23m. The schedules shown below are for the next available departures.
Want to know about travelling from La Mesa to Irvine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from La Mesa to Irvine. However, there are services departing from University Av & College Av station and arriving at Main-Harvard station via Old Town Transit Center station and Anaheim Regional Transportation Intermodal Center station. The journey, including transfers, takes approximately 4h 23m.
La Mesa to Irvine bus services, operated by San Diego Metro Transit, depart from University Av & College Av station.
La Mesa to Irvine bus services, operated by OCTA, arrive at Main-Harvard station.
The distance between La Mesa and Irvine is 124.9 km. The road distance is 143 km.
You can take a bus from University Av & College Av to Main-Harvard via Old Town Transit Center, San Diego, Anaheim Regional Transportation Intermodal Center, and Artic - Dock 4 in around 4h 39m.
