The average bus between La Mesa and La Jolla takes 1h 36m and the fastest bus takes 1h 20m. The bus runs at least 2 times per hour from La Mesa to La Jolla. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 30 minutes between La Mesa and La Jolla. The earliest departure is at 4:36 AM at night, and the last departure from La Mesa is at 9:47 PM which arrives into La Jolla at 11:16 PM. All services require a transfer, and take on average 1h 36m. The schedules shown below are for the next available departures.

1h 27m • 1 change

1h 20m • 1 change

1h 22m • 1 change

1h 24m • 1 change
Want to know about travelling from La Mesa to La Jolla? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from La Mesa to La Jolla. However, there are services departing from La Mesa station and arriving at La Jolla station via Old Town Transit Center. The journey, including transfers, takes approximately 1h 36m.
La Mesa to La Jolla bus services, operated by San Diego Metro Transit, depart from University Av & College Av station.
La Mesa to La Jolla bus services, operated by San Diego Metro Transit, arrive at Silverado St & Herschel Av station.
The distance between La Mesa and La Jolla is 25.1 km. The road distance is 32 km.
You can take a bus from University Av & College Av to Silverado St & Herschel Av via Old Town Transit Center in around 1h 45m.