The average bus between La Mesa and Los Angeles takes 4h 49m and the fastest bus takes 3h 46m. The bus service runs several times per day from La Mesa to Los Angeles. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between La Mesa and Los Angeles. The earliest departure is at 4:36 AM at night, and the last departure from La Mesa is at 10:19 PM which arrives into Los Angeles at 9:15 AM. All services require a transfer at 12th & Imperial Station and take an average of 4h 49m. The schedules shown below are for the next available departures.
Want to know about travelling from La Mesa to Los Angeles? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from La Mesa to Los Angeles. However, there are services departing from La Mesa station and arriving at Los Angeles station via Los Angeles Union Station station. The journey, including transfers, takes approximately 4h 49m.
La Mesa to Los Angeles bus services, operated by San Diego Metro Transit, depart from San Diego station.
La Mesa to Los Angeles bus services, operated by San Diego Metro Transit, arrive at Los Angeles Union Station.
The distance between La Mesa and Los Angeles is 182.3 km. The road distance is 217 km.
Greyhound Mexico operates a bus from San Diego to Los Angeles Union Station 3 times a day. Tickets cost $23–40 and the journey takes 2h 55m.