The average bus between La Mesa and Newport Beach takes 5h 39m and the fastest bus takes 4h 15m. The bus service runs several times per day from La Mesa to Newport Beach. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between La Mesa and Newport Beach. The earliest departure is at 7:30 AM in the morning, and the last departure from La Mesa is at 10:19 PM which arrives into Newport Beach at 12:17 PM. All services require a transfer at 12th & Imperial Station and take an average of 5h 39m. The schedules shown below are for the next available departures.



4h 15m • 3 changes



5h 11m • 3 changes
Arrives next day



5h 26m • 3 changes



4h 15m • 3 changes



5h 11m • 3 changes
Arrives next day



5h 26m • 3 changes
Arrives next day



13h 58m • 3 changes
Want to know about travelling from La Mesa to Newport Beach? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from La Mesa to Newport Beach. However, there are services departing from La Mesa station and arriving at Newport Beach station via Santa Ana. The journey, including transfers, takes approximately 5h 39m.
La Mesa to Newport Beach bus services, operated by San Diego Metro Transit, depart from San Diego station.
La Mesa to Newport Beach bus services, operated by San Diego Metro Transit, arrive at 17Th-Pomona station.
The distance between La Mesa and Newport Beach is 126.7 km. The road distance is 190 km.
You can take a vehicle from La Mesa Blvd Station to 17Th-Pomona via 12th & Imperial Station, San Diego, Santa Ana, The Depot At Santa Ana Dock 1, and Flower-6Th in around 5h 12m.