The average bus between La Seyne-sur-Mer and Lyon takes 6h 21m and the fastest bus takes 4h 54m. The bus service runs several times per day from La Seyne-sur-Mer to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between La Seyne-sur-Mer and Lyon. The earliest departure is at 6:17 AM in the morning, and the last departure from La Seyne-sur-Mer is at 11:42 PM which arrives into Lyon at 5:15 AM. All services require a transfer at Gare Routière and take an average of 6h 21m. The schedules shown below are for the next available departures.

6h 58m • 1 change
7h 16m • 1 change
6h 16m • 1 changeArrives next day

5h 9m • 1 change
6h 56m • 1 change
6h 50m • 1 change
6h 4m • 1 changeArrives next day

5h 15m • 1 change
6h 40m • 1 change
6h 59m • 1 change
6h 2m • 1 changeArrives next day

4h 54m • 1 change
6h 40m • 1 change
6h 59m • 1 change
6h 2m • 1 changeArrives next day

4h 54m • 1 change
6h 40m • 1 change
6h 59m • 1 change
6h 2m • 1 changeArrives next day

4h 54m • 1 change
6h 40m • 1 change
6h 59m • 1 change
6h 2m • 1 changeArrives next day

4h 54m • 1 changeWant to know about travelling from La Seyne-sur-Mer to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from La Seyne-sur-Mer to Lyon. However, there are services departing from La Seyne-sur-Mer station and arriving at Lyon station via Lyon - Gerland Bus Station station. The journey, including transfers, takes approximately 6h 21m.
La Seyne-sur-Mer to Lyon bus services, operated by RMTT - Toulon, depart from Toulon - Bus Station.
La Seyne-sur-Mer to Lyon bus services, operated by RMTT - Toulon, arrive at Lyon - Gerland Bus Station.
The distance between La Seyne-sur-Mer and Lyon is 305.3 km. The road distance is 386 km.
BlaBlaCar Bus operates a bus from Toulon - Bus Station to Lyon - Gerland Bus Station every 4 hours. Tickets cost €25–45 and the journey takes 4h 25m. FlixBus also services this route 3 times a day.