The average bus between La Seyne-sur-Mer and Lyon takes 5h 59m and the fastest bus takes 4h 46m. The bus service runs several times per day from La Seyne-sur-Mer to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between La Seyne-sur-Mer and Lyon. The earliest departure is at 12:04 AM at night, and the last departure from La Seyne-sur-Mer is at 11:45 PM which arrives into Lyon at 5:15 AM. All services require a transfer at Péri / Obs and take an average of 5h 59m. The schedules shown below are for the next available departures.

6h 28m • 1 change

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Want to know about travelling from La Seyne-sur-Mer to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from La Seyne-sur-Mer to Lyon. However, there are services departing from La Seyne-sur-Mer station and arriving at Lyon station via Lyon - Gerland Bus Station station. The journey, including transfers, takes approximately 5h 59m.
La Seyne-sur-Mer to Lyon bus services, operated by RMTT - Toulon, depart from Toulon - Bus Station.
La Seyne-sur-Mer to Lyon bus services, operated by RMTT - Toulon, arrive at Lyon - Gerland Bus Station.
The distance between La Seyne-sur-Mer and Lyon is 305.3 km. The road distance is 394 km.
BlaBlaCar Bus operates a bus from Toulon - Bus Station to Lyon - Gerland Bus Station 5 times a day. Tickets cost €30–60 and the journey takes 5h 35m. FlixBus also services this route 3 times a day.