The average bus between La Spezia and Roma Termini takes 6h 48m and the fastest bus takes 5h 43m. The bus service runs several times per day from La Spezia to Roma Termini. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between La Spezia and Roma Termini. The earliest departure is at 1:45 AM at night, and the last departure from La Spezia is at 11:00 PM which arrives into Roma Termini at 6:31 AM. All services require a transfer, and take on average 6h 48m. The schedules shown below are for the next available departures.

7h 7m • 1 change

6h 55m • 1 change
Arrives next day

7h 30m • 1 change

5h 58m • 1 change

7h 7m • 1 change

7h • 1 change

6h 55m • 1 change

5h 58m • 1 change

6h 56m • 1 change

7h • 1 change

6h 55m • 1 change

5h 43m • 1 change

6h 56m • 1 change

6h 54m • 1 change

6h 56m • 1 change

5h 59m • 1 change

7h 7m • 1 change

7h • 1 change

6h 56m • 1 change

5h 59m • 1 change

7h 7m • 1 change

7h • 1 change
Arrives next day

6h 20m • 1 change
Want to know about travelling from La Spezia to Roma Termini? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from La Spezia to Roma Termini. However, there are services departing from La Spezia station and arriving at Roma Termini station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 6h 48m.
La Spezia to Roma Termini bus services, operated by FlixBus, depart from La Spezia station.
La Spezia to Roma Termini bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between La Spezia and Roma Termini is 327.6 km. The road distance is 422 km.
FlixBus operates a bus from La Spezia to Roma, Autostazione Tiburtina 5 times a day. Tickets cost €35–60 and the journey takes 5h 15m.