The average bus between Lafayette and St. Louis takes 11h 48m and the fastest bus takes 10h 45m. There is at least one bus per day from Lafayette to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Lafayette and St. Louis. The earliest departure is at 1:30 PM in the afternoon, and the last departure from Lafayette is at 1:30 PM which arrives into St. Louis at 11:15 PM. All services require a transfer, and take on average 11h 48m. The schedules shown below are for the next available departures.
Want to know about travelling from Lafayette to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lafayette to St. Louis. However, there are services departing from Lafayette station and arriving at St. Louis station via Indianapolis Union Station station. The journey, including transfers, takes approximately 11h 48m.
Lafayette to St. Louis bus services, operated by Amtrak Thruway, depart from Lafayette Amtrak Station.
Lafayette to St. Louis bus services, operated by Amtrak Thruway, arrive at St Louis Bus Station.
Book your Lafayette to St. Louis bus tickets online with Amtrak Thruway and Greyhound USA.
The distance between Lafayette and St. Louis is 347.5 km. The road distance is 491 km.
You can take a bus from Lafayette Amtrak Station to St Louis Bus Station via Indianapolis Union Station in around 7h 15m.
