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Lake City to Kissimmee buses

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Trip Overview

The average bus between Lake City and Kissimmee takes 16h 7m and the fastest bus takes 11h 55m. There is at least one bus per day from Lake City to Kissimmee. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

16h 7m
Duration
222 mi
Distance
$42
Average price
Once daily
Frequency

Lake City to Kissimmee bus times

Buses run once daily between Lake City and Kissimmee. The earliest departure is at 1:45 PM in the afternoon, and the last departure from Lake City is at 7:30 PM which arrives into Kissimmee at 7:25 AM. All services require a transfer at Jacksonville and take an average of 16h 7m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida TransportLynx Central Florida Transport11h 55m • 3 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida TransportLynx Central Florida Transport11h 55m • 3 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida TransportLynx Central Florida Transport11h 55m • 3 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida TransportLynx Central Florida Transport17h 40m • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida TransportLynx Central Florida Transport11h 55m • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida TransportLynx Central Florida Transport12h 40m • 3 changes

Frequently asked questions

Want to know about travelling from Lake City to Kissimmee? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Lake City to Kissimmee.ExpandLaunch map view
  • Distance: 221.7 mi
  • Duration: 16h 7m

What companies run services between Lake City, FL, USA and Kissimmee, FL, USA?

You can take a bus from Lake City Bus Station to N John Young Pkwy & W Vine St via Jacksonville, Orlando Bus Station, John Young Pkwy & Amelia St, and Washington Shores Superstop in around 7h 21m.

Operators