Rome2Rio

Lake City to Kissimmee buses

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Trip Overview

The average bus between Lake City and Kissimmee takes 20h 19m and the fastest bus takes 20h 17m. The bus runs, on average, 6 times per week from Lake City to Kissimmee. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

20h 19m
Duration
222 mi
Distance
$44
Average price
6 times a week
Frequency

Lake City to Kissimmee bus times

Buses run 6 times a week between Lake City and Kissimmee. The service departs Lake City at 7:30 PM in the evening, which arrives into Kissimmee at 15:50:17. All services require a transfer at Jacksonville and take an average of 20h 19m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida Transport20h 20m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida Transport20h 20m • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida Transport20h 18m • 2 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida Transport20h 17m • 2 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida Transport20h 20m • 2 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida Transport20h 20m • 2 changes

Frequently asked questions

Want to know about travelling from Lake City to Kissimmee? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Lake City to Kissimmee.ExpandLaunch map view
  • Distance: 221.5 mi
  • Duration: 20h 19m

What companies run services between Lake City, FL, USA and Kissimmee, FL, USA?

You can take a bus from Lake City Bus Station to Kissimmee via Jacksonville, Orlando Bus Station, John Young Pkwy & Amelia St, N Garland Ave & W Amelia St, and LYNX Central in around 6h 30m.

Operators