The average bus between Lake City and Port Saint Lucie takes 16h 9m and the fastest bus takes 13h 15m. There is at least one bus per day from Lake City to Port Saint Lucie. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Lake City and Port Saint Lucie. The earliest departure is at 2:00 PM in the afternoon, and the last departure from Lake City is at 7:30 PM which arrives into Port Saint Lucie at 8:45 AM. All services require a transfer at Jacksonville and take an average of 16h 9m. The schedules shown below are for the next available departures.
Want to know about travelling from Lake City to Port Saint Lucie? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lake City to Port Saint Lucie. However, there are services departing from Lake City station and arriving at Port Saint Lucie station via Jacksonville. The journey, including transfers, takes approximately 16h 9m.
Lake City to Port Saint Lucie bus services, operated by Greyhound USA, depart from Lake City Bus Station.
Lake City to Port Saint Lucie bus services, operated by Greyhound USA, arrive at Fort Pierce station.
The distance between Lake City and Port Saint Lucie is 391.7 km. The road distance is 529 km.
You can take a bus from Lake City Bus Station to Fort Pierce via Jacksonville, Orlando Bus Station, John Young Pkwy & Amelia St, N Garland Ave & W Amelia St, L B Mcleod Rd & Gardenia Ave, and Orlando in around 9h 2m.
