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Lake City to Tampa buses

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Trip Overview

The average bus between Lake City and Tampa takes 10h 29m and the fastest bus takes 8h 40m. The bus service runs several times per day from Lake City to Tampa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 29m
Duration
241 mi
Distance
$86
Average price
Twice daily
Frequency

Lake City to Tampa bus times

Buses run twice daily between Lake City and Tampa. The earliest departure is at 1:45 PM in the afternoon, and the last departure from Lake City is at 7:30 PM which arrives into Tampa at 6:00 AM. All services require a transfer at Ruskin and take an average of 10h 29m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

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    Greyhound USAFlixbus USAFlixbus USA8h 40m • 2 changes
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    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA10h 30m • 2 changes

Departing Sunday, November 8, 2026

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    Greyhound USAFlixbus USAFlixbus USA8h 40m • 2 changes
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    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA10h 30m • 2 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA10h 30m • 2 changes

Departing Tuesday, November 10, 2026

  •  → 

    Greyhound USAFlixbus USAFlixbus USA8h 40m • 2 changes
  •  → 

    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA10h 30m • 2 changes

Departing Wednesday, November 11, 2026

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    Greyhound USAFlixbus USAFlixbus USA8h 40m • 2 changes
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    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA17h 45m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAFlixbus USAFlixbus USA10h 30m • 2 changes

Frequently asked questions

Want to know about travelling from Lake City to Tampa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Lake City to Tampa.ExpandLaunch map view
  • Distance: 241.4 mi
  • Duration: 10h 29m

What companies run services between Lake City, FL, USA and Tampa, FL, USA?

Omnibus Express operates a bus from Lake City to Ruskin once daily. Tickets cost $55–75 and the journey takes 3h 36m.

Operators