The average bus between Lake City and West Palm Beach takes 12h 57m and the fastest bus takes 8h 45m. The bus service runs several times per day from Lake City to West Palm Beach. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Lake City and West Palm Beach. The earliest departure is at 2:00 PM in the afternoon, and the last departure from Lake City is at 7:30 PM which arrives into West Palm Beach at 9:35 PM. All services require a transfer at Jacksonville and take an average of 12h 57m. The schedules shown below are for the next available departures.
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12h 10m • 2 changes
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8h 45m • 2 changes
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12h 10m • 2 changes
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8h 45m • 2 changes
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12h 10m • 2 changes
Arrives next day


8h 45m • 2 changes
Arrives next day


12h 10m • 2 changes
Arrives next day


8h 45m • 2 changes
Want to know about travelling from Lake City to West Palm Beach? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lake City to West Palm Beach. However, there are services departing from Lake City station and arriving at West Palm Beach station via Jacksonville. The journey, including transfers, takes approximately 12h 57m.
Lake City to West Palm Beach bus services, operated by Greyhound USA, depart from Lake City Bus Station.
Lake City to West Palm Beach bus services, operated by Greyhound USA, arrive at West Palm Beach Bus Station.
Book your Lake City to West Palm Beach bus tickets online with Greyhound USA and Flixbus USA.
The distance between Lake City and West Palm Beach is 461.6 km. The road distance is 608 km.
You can take a bus from Lake City Bus Station to West Palm Beach Bus Station via Jacksonville and Orlando Bus Station in around 9h 10m.