The average bus between Lake Ontario and Syracuse takes 6h 58m and the fastest bus takes 5h 56m. The bus service runs several times per day from Lake Ontario to Syracuse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Lake Ontario and Syracuse. The earliest departure is at 6:47 AM in the morning, and the last departure from Lake Ontario is at 9:23 PM which arrives into Syracuse at 3:20 AM. All services require a transfer at Bay St at Lake Shore Blvd W and take an average of 6h 58m. The schedules shown below are for the next available departures.
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7h 9m • 1 change
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6h 54m • 1 change

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7h 7m • 1 change
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6h 58m • 1 change
Want to know about travelling from Lake Ontario to Syracuse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lake Ontario to Syracuse. However, there are services departing from Lake Ontario station and arriving at Syracuse station via Syracuse Bus Station station. The journey, including transfers, takes approximately 6h 58m.
Lake Ontario to Syracuse bus services, operated by Toronto Transit Commission (TTC), depart from Toronto station.
Lake Ontario to Syracuse bus services, operated by Toronto Transit Commission (TTC), arrive at Syracuse Bus Station.
The distance between Lake Ontario and Syracuse is 168.8 km. The road distance is 399 km.
Greyhound USA operates a bus from Toronto to Syracuse Bus Station 3 times a day. Tickets cost $35–70 and the journey takes 5h 50m. Flixbus USA also services this route twice daily.