The average bus between Larissa and Sérres takes 5h 2m and the fastest bus takes 4h. The bus service runs several times per day from Larissa to Sérres. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Larissa and Sérres. The earliest departure is at 5:15 AM in the morning, and the last departure from Larissa is at 8:30 PM which arrives into Sérres at 9:15 AM. All services require a transfer, and take on average 5h 2m. The schedules shown below are for the next available departures.

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4h 45m • 1 change

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4h 45m • 1 change
Want to know about travelling from Larissa to Sérres? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Larissa to Sérres. However, there are services departing from Larissa station and arriving at Sérres station via Thessaloniki Macedonia KTEL Bus Station station. The journey, including transfers, takes approximately 5h 2m.
Larissa to Sérres bus services, operated by KTEL Larisas, depart from Larissa station.
Larissa to Sérres bus services, operated by KTEL Larisas, arrive at Serres station.
The distance between Larissa and Sérres is 187.3 km. The road distance is 230 km.
You can take a bus from Larissa to Serres via Thessaloniki Macedonia KTEL Bus Station in around 4h 30m.