The average bus between Larissa and Xánthi takes 6h 39m and the fastest bus takes 5h 45m. The bus service runs several times per day from Larissa to Xánthi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Larissa and Xánthi. The earliest departure is at 5:15 AM in the morning, and the last departure from Larissa is at 8:30 PM which arrives into Xánthi at 2:59 AM. All services require a transfer, and take on average 6h 39m. The schedules shown below are for the next available departures.

5h 45m • 1 change

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6h 30m • 1 change

5h 45m • 1 change

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Want to know about travelling from Larissa to Xánthi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Larissa to Xánthi. However, there are services departing from Larissa station and arriving at Xánthi station via Thessaloniki Macedonia KTEL Bus Station station. The journey, including transfers, takes approximately 6h 39m.
Larissa to Xánthi bus services, operated by KTEL Larisas, depart from Larissa station.
Larissa to Xánthi bus services, operated by KTEL Larisas, arrive at Xánthi station.
The distance between Larissa and Xánthi is 267.4 km. The road distance is 351 km.
You can take a bus from Larissa to Xánthi via Thessaloniki Macedonia KTEL Bus Station in around 6h 30m.