The average bus between Las Vegas and Guadalupe takes 22h 47m and the fastest bus takes 20h 40m. The bus service runs several times per day from Las Vegas to Guadalupe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Las Vegas and Guadalupe. The earliest departure is at 6:30 AM in the morning, and the last departure from Las Vegas is at 11:50 AM which arrives into Guadalupe at 10:30 AM. All services require a transfer at Los Angeles Downtown and take an average of 22h 47m. The schedules shown below are for the next available departures.
Arrives next day




24h • 4 changes
Arrives next day




20h 40m • 4 changes
Arrives next day




24h • 4 changes
Arrives next day




23h 40m • 4 changes
Arrives next day




24h • 4 changes
Arrives next day




20h 40m • 4 changes
Want to know about travelling from Las Vegas to Guadalupe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Las Vegas to Guadalupe. However, there are services departing from Las Vegas station and arriving at Guadalupe station via Los Angeles Downtown. The journey, including transfers, takes approximately 22h 47m.
Las Vegas to Guadalupe bus services, operated by Flixbus USA, depart from Las Vegas Downtown station.
Las Vegas to Guadalupe bus services, operated by Flixbus USA, arrive at Santa Maria Airport, CA station.
The distance between Las Vegas and Guadalupe is 509.3 km. The road distance is 759 km.
You can take a bus from Las Vegas Downtown to Guadalupe Amtrak Station via Los Angeles Downtown, Los Angeles Union Station, Los Angeles Airport, CA, Santa Maria Airport, CA, Santa Maria Public Airport, and Transit Center in around 13h 42m.