The average bus between Las Vegas and Otay Mesa takes 12h 36m and the fastest bus takes 11h 31m. The bus runs, on average, 5 times per week from Las Vegas to Otay Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between Las Vegas and Otay Mesa. The earliest departure is at 2:40 AM at night, and the last departure from Las Vegas is at 7:54 AM which arrives into Otay Mesa at 7:54 PM. All services require a transfer at San Ysidro, CA and take an average of 12h 36m. The schedules shown below are for the next available departures.
Want to know about travelling from Las Vegas to Otay Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Las Vegas to Otay Mesa. However, there are services departing from Las Vegas station and arriving at Otay Mesa station via San Ysidro, CA. The journey, including transfers, takes approximately 12h 36m.
Las Vegas to Otay Mesa bus services, operated by RTC Southern Nevada, depart from Las Vegas station.
Las Vegas to Otay Mesa bus services, operated by RTC Southern Nevada, arrive at San Ysidro, CA station.
The distance between Las Vegas and Otay Mesa is 436.1 km. The road distance is 694 km.
Tufesa operates a bus from Las Vegas to San Ysidro, CA twice daily. Tickets cost $80–110 and the journey takes 7h.
