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Lazio to Brindisi buses

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Trip Overview

The average bus between Lazio and Brindisi takes 10h 11m and the fastest bus takes 8h 45m. The bus service runs several times per day from Lazio to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 11m
Duration
543 km
Distance
€56
Average price
Twice daily
Frequency

Lazio to Brindisi bus times

Buses run twice daily between Lazio and Brindisi. The earliest departure is at 6:45 AM in the morning, and the last departure from Lazio is at 4:20 PM which arrives into Brindisi at 6:10 AM. All services require a transfer, and take on average 10h 11m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

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    Cotral S.p.A.FlixBus9h 54m • 1 change

Departing Thursday, November 5, 2026

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    Cotral S.p.A.FlixBus9h 54m • 1 change

Departing Friday, November 6, 2026

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    Cotral S.p.A.FlixBus9h 54m • 1 change

Departing Saturday, November 7, 2026

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    ATAC S.p.A. Azienda per la mobilitàFlixBus9h 40m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus9h 14m • 1 change
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    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 45m • 1 change
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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus13h 50m • 1 change

Departing Sunday, November 8, 2026

  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus9h 40m • 1 change
  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus9h 14m • 1 change
  •  → 

    ATAC S.p.A. Azienda per la mobilitàFlixBus8h 45m • 1 change
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    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBus13h 50m • 1 change

Departing Monday, November 9, 2026

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    Cotral S.p.A.FlixBus9h 54m • 1 change

Departing Tuesday, November 10, 2026

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    Cotral S.p.A.FlixBus9h 54m • 1 change

Frequently asked questions

Want to know about travelling from Lazio to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Lazio to Brindisi.ExpandLaunch map view
  • Distance: 542.8 km
  • Duration: 10h 11m

What companies run services between Lazio, Italy and Brindisi, Italy?

FlixBus operates a bus from Roma, Autostazione Tiburtina to Brindisi 5 times a day. Tickets cost €45–75 and the journey takes 7h 25m.

Operators