The average bus between Lecce and Sant'Isidoro a Capo le Case takes 8h 58m and the fastest bus takes 7h 54m. The bus service runs several times per day from Lecce to Sant'Isidoro a Capo le Case. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Lecce and Sant'Isidoro a Capo le Case. The earliest departure is at 5:00 AM in the morning, and the last departure from Lecce is at 10:55 PM which arrives into Sant'Isidoro a Capo le Case at 7:27 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 8h 58m. The schedules shown below are for the next available departures.

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Want to know about travelling from Lecce to Sant'Isidoro a Capo le Case? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lecce to Sant'Isidoro a Capo le Case. However, there are services departing from Lecce station and arriving at Sant'Isidoro a Capo le Case station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 8h 58m.
Lecce to Sant'Isidoro a Capo le Case bus services, operated by FlixBus, depart from Lecce station.
Lecce to Sant'Isidoro a Capo le Case bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Lecce and Sant'Isidoro a Capo le Case is 506.4 km. The road distance is 617 km.
FlixBus operates a bus from Lecce to Roma, Autostazione Tiburtina every 4 hours. Tickets cost €50–90 and the journey takes 8h 15m.