The average bus between Leiden and Brussels takes 4h 20m and the fastest bus takes 3h 33m. The bus service runs several times per day from Leiden to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Leiden and Brussels. The earliest departure is at 12:24 AM at night, and the last departure from Leiden is at 10:25 PM which arrives into Brussels at 2:35 AM. All services require a transfer at Den Haag, Den Haag Centraal and take an average of 4h 20m. The schedules shown below are for the next available departures.

4h 28m • 1 change

4h 3m • 1 change
Arrives next day

4h 18m • 1 change
Arrives next day

3h 33m • 1 change

3h 41m • 1 change

4h 10m • 1 change

4h 23m • 1 change

4h 28m • 1 change

3h 41m • 1 change

4h 23m • 1 change

4h 28m • 1 change

4h 3m • 1 change

3h 41m • 1 change

4h 18m • 1 change

4h 23m • 1 change

4h 28m • 1 change

3h 41m • 1 change

4h 10m • 1 change

4h 18m • 1 change

4h 23m • 1 change

9h 55m • 1 change

4h 26m • 1 change

4h 19m • 1 change

4h 38m • 1 change

9h 24m • 1 change

4h 18m • 1 change

4h 38m • 1 change

4h 43m • 1 change
Want to know about travelling from Leiden to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Leiden to Brussels. However, there are services departing from Leiden station and arriving at Brussels station via Brussels-North train station station. The journey, including transfers, takes approximately 4h 20m.
Leiden to Brussels bus services, operated by RRReis, depart from The Hague station.
Leiden to Brussels bus services, operated by RRReis, arrive at Brussels-North train station.
The distance between Leiden and Brussels is 145.8 km. The road distance is 184 km.
FlixBus operates a bus from The Hague to Brussels-North train station every 3 hours. Tickets cost €14–23 and the journey takes 3h 20m.