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Lewiston to Buffalo buses

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Trip Overview

The bus between Lewiston and Buffalo takes 33h 50m. The bus runs, on average, 6 times per week from Lewiston to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

33h 50m
Duration
619 mi
Distance
$131
Average price
6 times a week
Frequency

Lewiston to Buffalo bus times

Buses run 6 times a week between Lewiston and Buffalo. The service departs Lewiston at 12:45 PM in the afternoon, which arrives into Buffalo at 22:35:00. All services require a transfer, and take on average 33h 50m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

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    Arrives next day

    Greyhound USAGreyhound USA33h 50m • 1 change

Departing Tuesday, November 3, 2026

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    Arrives next day

    Greyhound USAGreyhound USA33h 50m • 1 change

Departing Wednesday, November 4, 2026

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    Arrives next day

    Greyhound USAGreyhound USA33h 50m • 1 change

Departing Thursday, November 5, 2026

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    Arrives next day

    Greyhound USAGreyhound USA33h 50m • 1 change

Departing Friday, November 6, 2026

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    Arrives next day

    Greyhound USAGreyhound USA33h 50m • 1 change

Departing Saturday, November 7, 2026

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    Arrives next day

    Greyhound USAGreyhound USA33h 50m • 1 change

Frequently asked questions

Want to know about travelling from Lewiston to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Lewiston to Buffalo.ExpandLaunch map view
  • Distance: 618.9 mi
  • Duration: 33h 50m

What companies run services between Lewiston, ME, USA and Buffalo, NY, USA?

You can take a bus from Lewiston Bus Stop to Buffalo via Boston in around 14h 35m.

Operators