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Lewiston to Hyannis buses

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Trip Overview

The bus between Lewiston and Hyannis takes 5h 30m. There is at least one bus per day from Lewiston to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 30m
Duration
216 mi
Distance
$61
Average price
Once daily
Frequency

Lewiston to Hyannis bus times

Buses run once daily between Lewiston and Hyannis. The service departs Lewiston at 12:45 PM in the afternoon, which arrives into Hyannis at 18:15:00. All services require a transfer at Boston and take an average of 5h 30m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

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    Greyhound USAPlymouth & Brockton5h 30m • 1 change

Departing Saturday, November 7, 2026

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    Greyhound USAPlymouth & Brockton5h 30m • 1 change

Departing Sunday, November 8, 2026

  •  → 

    Greyhound USAPlymouth & Brockton5h 30m • 1 change

Departing Monday, November 9, 2026

  •  → 

    Greyhound USAPlymouth & Brockton5h 30m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    Greyhound USAPlymouth & Brockton5h 30m • 1 change

Departing Wednesday, November 11, 2026

  •  → 

    Greyhound USAPlymouth & Brockton5h 30m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Greyhound USAPlymouth & Brockton5h 30m • 1 change

Frequently asked questions

Want to know about travelling from Lewiston to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Lewiston to Hyannis.ExpandLaunch map view
  • Distance: 216.5 mi
  • Duration: 5h 30m

What companies run services between Lewiston, ME, USA and Hyannis, MA, USA?

You can take a bus from Lewiston Bus Stop to Hyannis Transportation Center via Boston and Boston South Buses in around 6h 2m.

Operators