The average bus between Lille and Lyon takes 14h 21m and the fastest bus takes 14h 8m. The bus service runs several times per day from Lille to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Lille and Lyon. The earliest departure is at 7:05 PM in the evening, and the last departure from Lille is at 9:08 PM which arrives into Lyon at 11:20 AM. All services require a transfer at Oostmalle Busstation perron 3 and take an average of 14h 21m. The schedules shown below are for the next available departures.
Arrives next day


14h 9m • 2 changesArrives next day


15h 13m • 2 changesArrives next day


14h 10m • 2 changesArrives next day


14h 15m • 2 changesArrives next day


14h 8m • 2 changesArrives next day


14h 12m • 2 changesWant to know about travelling from Lille to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lille to Lyon. However, there are services departing from Lille station and arriving at Lyon station via Lyon - Gerland Bus Station station. The journey, including transfers, takes approximately 14h 21m.
Lille to Lyon bus services, operated by De Lijn, depart from Antwerp - Rooseveltplaats station.
Lille to Lyon bus services, operated by De Lijn, arrive at Lyon - Gerland Bus Station.
The distance between Lille and Lyon is 610.9 km. The road distance is 811 km.
BlaBlaCar Bus operates a bus from Antwerp - Rooseveltplaats to Lyon - Gerland Bus Station twice daily. Tickets cost €50–85 and the journey takes 10h 45m. FlixBus also services this route 4 times a week.