The average bus between Lille and Lyon takes 14h 2m and the fastest bus takes 13h 36m. The bus service runs several times per day from Lille to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Lille and Lyon. The earliest departure is at 6:40 PM in the evening, and the last departure from Lille is at 9:40 PM which arrives into Lyon at 11:20 AM. All services require a transfer at Vorselaar Voetbalterrein and take an average of 14h 2m. The schedules shown below are for the next available departures.
Arrives next day


14h 35m • 2 changes
Arrives next day


13h 40m • 2 changes
Arrives next day


14h 35m • 2 changes
Arrives next day


13h 40m • 2 changes
Arrives next day


14h 35m • 2 changes
Arrives next day


13h 40m • 2 changes
Want to know about travelling from Lille to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lille to Lyon. However, there are services departing from Lille station and arriving at Lyon station via Lyon. The journey, including transfers, takes approximately 14h 2m.
Lille to Lyon bus services, operated by De Lijn, depart from Waypoint Antwerp Noorderplaats station.
Lille to Lyon bus services, operated by De Lijn, arrive at Lyon station.
The distance between Lille and Lyon is 610.9 km. The road distance is 835 km.
FlixBus operates a bus from Waypoint Antwerp Noorderplaats to Lyon once daily. Tickets cost €65–120 and the journey takes 11h 50m.