The average bus between Lille and Milan takes 16h 8m and the fastest bus takes 15h 20m. The bus service runs several times per day from Lille to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Lille and Milan. The earliest departure is at 5:39 PM in the evening, and the last departure from Lille is at 8:40 PM which arrives into Milan at 1:10 PM. All services require a transfer at Vorselaar Voetbalterrein and take an average of 16h 8m. The schedules shown below are for the next available departures.
Arrives next day


15h 20m • 2 changes
Arrives next day


16h 30m • 2 changes
Arrives next day


15h 51m • 2 changes
Arrives next day


17h 31m • 2 changes
Arrives next day


15h 51m • 2 changes
Arrives next day


17h 31m • 2 changes
Arrives next day


15h 20m • 2 changes
Arrives next day


16h 30m • 2 changes
Arrives next day


15h 20m • 2 changes
Arrives next day


16h 30m • 2 changes
Want to know about travelling from Lille to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lille to Milan. However, there are services departing from Lille station and arriving at Milan station via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 16h 8m.
Lille to Milan bus services, operated by De Lijn, depart from Antwerp - Rooseveltplaats station.
Lille to Milan bus services, operated by De Lijn, arrive at Milano, Autostazione Lampugnano station.
The distance between Lille and Milan is 718.6 km. The road distance is 993 km.
BlaBlaCar Bus operates a bus from Antwerp - Rooseveltplaats to Milano, Autostazione Lampugnano twice daily. Tickets cost €85–150 and the journey takes 13h 50m.