The average bus between Lisbon Orient Station and Santiago do Cacém takes 2h 23m and the fastest bus takes 2h 5m. The bus service runs several times per day from Lisbon Orient Station to Santiago do Cacém. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Lisbon Orient Station and Santiago do Cacém. The earliest departure is at 2:00 AM at night, and the last departure from Lisbon Orient Station is at 7:30 PM which arrives into Santiago do Cacém at 9:40 PM. All services require a transfer at Interface de Transportes de Setúbal P1 and take an average of 2h 23m. The schedules shown below are for the next available departures.

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Want to know about travelling from Lisbon Orient Station to Santiago do Cacém? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lisbon Orient Station to Santiago do Cacém. However, there are services departing from Lisbon Orient Station station and arriving at Santiago do Cacém station via Interface de Transportes de Setúbal P1. The journey, including transfers, takes approximately 2h 23m.
Lisbon Orient Station to Santiago do Cacém bus services, operated by Carris Metropolitana, depart from Estação Rodoviária de Lisboa Oriente station.
Lisbon Orient Station to Santiago do Cacém bus services, operated by Carris Metropolitana, arrive at Terminal Rodoviário de Santiago do Cacém station.
Book your Lisbon Orient Station to Santiago do Cacém bus tickets online with Carris Metropolitana and Rede Expressos.
The distance between Lisbon Orient Station and Santiago do Cacém is 90.6 km. The road distance is 124 km.
You can take a bus from Estação Rodoviária de Lisboa Oriente to Terminal Rodoviário de Santiago do Cacém via Interface de Transportes de Setúbal P1 and Interface de Transportes de Setúbal in around 3h 2m.