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Lisbon Region to Prague buses

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Trip Overview

The average bus between Lisbon Region and Prague takes 41h 36m and the fastest bus takes 41h 16m. The bus runs, on average, 5 times per week from Lisbon Region to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

41h 36m
Duration
2,966 km
Distance
Kč 7,351
Average price
5 times a week
Frequency

Lisbon Region to Prague bus times

Buses run 5 times a week between Lisbon Region and Prague. The earliest departure is at 2:27 PM in the afternoon, and the last departure from Lisbon Region is at 2:38 PM which arrives into Prague at 8:55 AM. All services require a transfer at Estação Oriente and take an average of 41h 36m. The schedules shown below are for the next available departures.

Departing Wednesday, October 21, 2026

  •  → 

    Arrives +2 days

    CarrisFlixBusFlixBus41h 27m • 2 changes

Departing Thursday, October 22, 2026

  •  → 

    Arrives +2 days

    CarrisFlixBusFlixBus41h 27m • 2 changes

Departing Friday, October 23, 2026

  •  → 

    Arrives +2 days

    CarrisFlixBusFlixBus41h 27m • 2 changes

Departing Saturday, October 24, 2026

  •  → 

    Arrives +2 days

    CarrisFlixBusFlixBus42h 25m • 2 changes

Departing Sunday, October 25, 2026

  •  → 

    Arrives +2 days

    CarrisFlixBusFlixBus41h 16m • 2 changes

Frequently asked questions

Want to know about travelling from Lisbon Region to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Lisbon Region to Prague.ExpandLaunch map view
  • Distance: 2,966.2 km
  • Duration: 41h 36m

What companies run services between Lisbon Region, Portugal and Prague, Czechia?

You can take a bus from Sul e Sueste to Prague via Estação Oriente, Lisbon - Oriente, and Lyon in around 42h 5m.

Operators