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Lisbon to Siena buses

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Trip Overview

The average bus between Lisbon and Siena takes 37h 27m and the fastest bus takes 34h 20m. The bus runs, on average, 6 times per week from Lisbon to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

37h 27m
Duration
2,424 km
Distance
€254
Average price
6 times a week
Frequency

Lisbon to Siena bus times

Buses run 6 times a week between Lisbon and Siena. The service departs Lisbon at 9:35 AM in the morning, which arrives into Siena at 15:40:00. All services require a transfer, and take on average 37h 27m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus2d 5h • 1 change

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    FlixBusFlixBus34h 20m • 1 change

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    FlixBusFlixBus34h 20m • 1 change

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    FlixBusFlixBus34h 20m • 1 change

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    FlixBusFlixBus34h 20m • 1 change

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    FlixBusFlixBus34h 20m • 1 change

Frequently asked questions

Want to know about travelling from Lisbon to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Lisbon to Siena.ExpandLaunch map view
  • Distance: 2,423.5 km
  • Duration: 37h 27m

What companies run services between Lisbon, Portugal and Siena, Italy?

You can take a bus from Lisbon to Siena via Genoa in around 34h 30m.

Operators