The average bus between Lisse and Brussels takes 4h 53m and the fastest bus takes 4h. There is a bus service every few hours from Lisse to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Lisse and Brussels. The earliest departure is at 5:15 AM in the morning, and the last departure from Lisse is at 10:44 PM which arrives into Brussels at 7:05 AM. All services require a transfer at Schiphol, Airport/Plaza and take an average of 4h 53m. The schedules shown below are for the next available departures.


4h 27m • 2 changes


4h 40m • 2 changes


4h 25m • 2 changes


4h 28m • 2 changes


4h 30m • 2 changes


4h 27m • 2 changes


4h 40m • 2 changes


4h 25m • 2 changes


4h 30m • 2 changes


4h 27m • 2 changes


4h 40m • 2 changes


4h 25m • 2 changes
Want to know about travelling from Lisse to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lisse to Brussels. However, there are services departing from Lisse station and arriving at Brussels station via Brussels-North train station station. The journey, including transfers, takes approximately 4h 53m.
Lisse to Brussels bus services, operated by Qbuzz B.V., depart from Amsterdam Sloterdijk station.
Lisse to Brussels bus services, operated by Qbuzz B.V., arrive at Brussels-North train station.
The distance between Lisse and Brussels is 157.4 km. The road distance is 245 km.
FlixBus operates a bus from Amsterdam Sloterdijk to Brussels-North train station hourly. Tickets cost €17–28 and the journey takes 2h 45m.