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Littleton to Chicago buses

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Trip Overview

The bus between Littleton and Chicago takes 42h 30m. The bus runs, on average, 5 times per week from Littleton to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

42h 30m
Duration
1,363 mi
Distance
$271
Average price
5 times a week
Frequency

Littleton to Chicago bus times

Buses run 5 times a week between Littleton and Chicago. The service departs Littleton at 12:40 PM in the afternoon, which arrives into Chicago at 06:10:00. All services require a transfer at Boston - South Station and take an average of 42h 30m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    Concord Coach LinesFlixbus USAFlixbus USA42h 30m • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    Concord Coach LinesFlixbus USAFlixbus USA42h 30m • 2 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives +2 days

    Concord Coach LinesFlixbus USAFlixbus USA42h 30m • 2 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    Concord Coach LinesFlixbus USAFlixbus USA42h 30m • 2 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    Concord Coach LinesFlixbus USAFlixbus USA42h 30m • 2 changes

Frequently asked questions

Want to know about travelling from Littleton to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Littleton to Chicago.ExpandLaunch map view
  • Distance: 1,363.3 mi
  • Duration: 42h 30m

What companies run services between Littleton, NH, USA and Chicago, IL, USA?

You can take a bus from Littleton to Chicago Bus Station via Boston - South Station, Boston, and New York Midtown in around 30h 2m.

Operators