The average bus between London Paddington and Aylesbury takes 3h 58m and the fastest bus takes 3h 20m. The bus service runs several times per day from London Paddington to Aylesbury. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between London Paddington and Aylesbury. The earliest departure is at 3:16 AM at night, and the last departure from London Paddington is at 3:15 PM which arrives into Aylesbury at 7:12 PM. All services require a transfer, and take on average 3h 58m. The schedules shown below are for the next available departures.

4h 2m • 1 change

4h 6m • 1 change

4h 6m • 1 change

4h 6m • 1 change

4h • 1 change

4h • 1 change

3h 50m • 1 change

4h 2m • 1 change

4h • 1 change

4h • 1 change

3h 50m • 1 change

4h 2m • 1 change

4h • 1 change

4h • 1 change

3h 50m • 1 change

4h 2m • 1 change

4h • 1 change

3h 50m • 1 change

4h 2m • 1 change

4h 6m • 1 change
Want to know about travelling from London Paddington to Aylesbury? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from London Paddington to Aylesbury. However, there are services departing from London Paddington station and arriving at Aylesbury station via Airport Bus Station station. The journey, including transfers, takes approximately 3h 58m.
London Paddington to Aylesbury bus services, operated by National Express, depart from Paddington Station.
London Paddington to Aylesbury bus services, operated by National Express, arrive at High Street station.
The distance between London Paddington and Aylesbury is 55.2 km. The road distance is 99 km.
You can take a bus from Paddington Station to High Street via Airport Bus Station in around 3h 47m.