The average bus between Los Angeles and La Mesa takes 6h 27m and the fastest bus takes 3h 51m. There is at least one bus per day from Los Angeles to La Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Los Angeles and La Mesa. The earliest departure is at 2:35 AM at night, and the last departure from Los Angeles is at 2:35 AM which arrives into La Mesa at 6:34 AM. All services require a transfer at San Diego and take an average of 6h 27m. The schedules shown below are for the next available departures.
Want to know about travelling from Los Angeles to La Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Los Angeles to La Mesa. However, there are services departing from Los Angeles station and arriving at La Mesa station via San Diego. The journey, including transfers, takes approximately 6h 27m.
Los Angeles to La Mesa bus services, operated by Amtrak, depart from Los Angeles Union Station.
Los Angeles to La Mesa bus services, operated by Amtrak, arrive at San Diego station.
The distance between Los Angeles and La Mesa is 182.3 km. The road distance is 218 km.
Greyhound Mexico operates a bus from Los Angeles Union Station to San Diego 3 times a day. Tickets cost $24–40 and the journey takes 2h 55m.
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