The average bus between Los Angeles and Otay Mesa takes 4h 43m and the fastest bus takes 3h 49m. The bus service runs several times per day from Los Angeles to Otay Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Los Angeles and Otay Mesa. The earliest departure is at 2:15 AM at night, and the last departure from Los Angeles is at 2:15 PM which arrives into Otay Mesa at 6:09 PM. All services require a transfer at San Ysidro, CA and take an average of 4h 43m. The schedules shown below are for the next available departures.
Want to know about travelling from Los Angeles to Otay Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Los Angeles to Otay Mesa. However, there are services departing from Los Angeles station and arriving at Otay Mesa station via San Ysidro, CA. The journey, including transfers, takes approximately 4h 43m.
Los Angeles to Otay Mesa bus services, operated by Tufesa, depart from Downtown Los Angeles station.
Los Angeles to Otay Mesa bus services, operated by Tufesa, arrive at San Ysidro, CA station.
The distance between Los Angeles and Otay Mesa is 202.6 km. The road distance is 231 km.
Tufesa operates a bus from Downtown Los Angeles to San Ysidro, CA 3 times a day. Tickets cost $40–65 and the journey takes 2h 45m.
