- Distance: 304.6 mi
- Duration: 6h 36m
The average bus between Louisville, KY and Chicago takes 6h 36m and the fastest bus takes 5h 10m. The bus service runs several times per day from Louisville, KY to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Louisville, KY and Chicago. The earliest departure is at 2:55 AM at night, and the last departure from Louisville, KY is at 8:00 PM which arrives into Chicago at 12:10 AM. All services run direct with no transfers required, and take on average 6h 36m. The schedules shown below are for the next available departures.
Want to know about travelling from Louisville, KY to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Louisville, KY station and arriving at Chicago station. Services depart every 4 hours, and operate 3 times a day. The journey takes approximately 6h 36m.
Louisville, KY to Chicago bus services, operated by Amtrak Thruway, depart from Louisville Bus Station.
Louisville, KY to Chicago bus services, operated by Amtrak Thruway, arrive at Chicago Bus Station.
Book your Louisville, KY to Chicago bus tickets online with Amtrak Thruway, Greyhound USA and Flixbus USA.
The distance between Louisville, KY and Chicago is 433.1 km. The road distance is 490 km.
Greyhound USA operates a bus from Louisville Bus Station to Chicago Bus Station 4 times a day. Tickets cost $45–95 and the journey takes 7h 35m. Two other operators also service this route.
