The bus between Louisville, KY and St. Louis takes 8h 25m. There is at least one bus per day from Louisville, KY to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Louisville, KY and St. Louis. The earliest departure is at 8:30 AM in the morning, and the last departure from Louisville, KY is at 8:30 AM which arrives into St. Louis at 3:55 PM. All services require a transfer at Evansville and take an average of 8h 25m. The schedules shown below are for the next available departures.
Want to know about travelling from Louisville, KY to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Louisville, KY to St. Louis. However, there are services departing from Louisville, KY station and arriving at St. Louis station via Evansville. The journey, including transfers, takes approximately 8h 25m.
Louisville, KY to St. Louis bus services, operated by Jefferson Lines, depart from Louisville station.
Louisville, KY to St. Louis bus services, operated by Jefferson Lines, arrive at St Louis Bus Station.
The distance between Louisville, KY and St. Louis is 387.7 km. The road distance is 461 km.
You can take a bus from Louisville to St Louis Bus Station via Evansville and Evansville Bus Station in around 6h 40m.
