The bus between Louisville and Des Moines takes 17h. There is at least one bus per day from Louisville to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Louisville and Des Moines. The earliest departure is at 2:55 AM at night, and the last departure from Louisville is at 2:55 AM which arrives into Des Moines at 6:55 PM. All services require a transfer, and take on average 17h. The schedules shown below are for the next available departures.
Want to know about travelling from Louisville to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Louisville to Des Moines. However, there are services departing from Louisville station and arriving at Des Moines station via Indianapolis Union Station station. The journey, including transfers, takes approximately 17h.
Louisville to Des Moines bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
Louisville to Des Moines bus services, operated by Amtrak Thruway, arrive at Des Moines station.
Book your Louisville to Des Moines bus tickets online with Amtrak Thruway and Greyhound USA.
The distance between Louisville and Des Moines is 765.4 km. The road distance is 927 km.
You can take a bus from Louisville, KY to Des Moines via Indianapolis Union Station in around 13h 15m.
