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Louisville to Effingham buses

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Trip Overview

The average bus between Louisville and Effingham takes 6h 22m and the fastest bus takes 5h 15m. The bus service runs several times per day from Louisville to Effingham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 22m
Duration
257 mi
Distance
$53
Average price
Twice daily
Frequency

Louisville to Effingham bus times

Buses run twice daily between Louisville and Effingham. The earliest departure is at 8:35 AM in the morning, and the last departure from Louisville is at 2:45 PM which arrives into Effingham at 9:15 PM. All services require a transfer, and take on average 6h 22m. The schedules shown below are for the next available departures.

Departing Saturday, October 10, 2026

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    Greyhound USAGreyhound USA7h 30m • 1 change

Departing Sunday, October 11, 2026

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    Greyhound USAGreyhound USA5h 15m • 1 change
  •  → 

    Greyhound USAGreyhound USA7h 30m • 1 change

Departing Monday, October 12, 2026

  •  → 

    Greyhound USAGreyhound USA5h 15m • 1 change
  •  → 

    Greyhound USAGreyhound USA7h 30m • 1 change

Departing Tuesday, October 13, 2026

  •  → 

    Greyhound USAGreyhound USA5h 15m • 1 change
  •  → 

    Greyhound USAGreyhound USA7h 30m • 1 change

Departing Wednesday, October 14, 2026

  •  → 

    Greyhound USAGreyhound USA5h 15m • 1 change
  •  → 

    Greyhound USAGreyhound USA7h 30m • 1 change

Departing Thursday, October 15, 2026

  •  → 

    Greyhound USAGreyhound USA5h 15m • 1 change
  •  → 

    Greyhound USAGreyhound USA7h 30m • 1 change

Departing Friday, October 16, 2026

  •  → 

    Greyhound USAGreyhound USA5h 15m • 1 change
  •  → 

    Greyhound USAGreyhound USA7h 30m • 1 change

Frequently asked questions

Want to know about travelling from Louisville to Effingham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Louisville to Effingham.ExpandLaunch map view
  • Distance: 257.1 mi
  • Duration: 6h 22m

What companies run services between Louisville, KY, USA and Effingham, IL, USA?

You can take a bus from Louisville Bus Station to Effingham via Indianapolis Union Station in around 5h 35m.

Operators