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Louisville to Florence buses

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Trip Overview

The average bus between Louisville and Florence takes 17h 43m and the fastest bus takes 15h 5m. The bus service runs several times per day from Louisville to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

17h 43m
Duration
721 mi
Distance
$137
Average price
Twice daily
Frequency

Bus

best
  1. Take the bus from Louisville Bus Station to Atlanta Bus Stationbus bus Greyhound US0135 / ...
  2. Take the bus from Atlanta to Florencebus bus Ses 987 / ...
15h 20m
$110–212

Louisville to Florence bus times

Buses run twice daily between Louisville and Florence. The earliest departure is at 1:55 PM in the afternoon, and the last departure from Louisville is at 10:15 PM which arrives into Florence at 1:20 PM. All services require a transfer, and take on average 17h 43m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Louisville to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Louisville to Florence.ExpandLaunch map view
  • Distance: 720.6 mi
  • Duration: 17h 43m

What companies run services between Louisville, KY, USA and Florence, SC, USA?

You can take a bus from Louisville Bus Station to Florence via Atlanta in around 15h 20m.

Operators