Rome2Rio

Louisville to Hamilton buses

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Trip Overview

The average bus between Louisville and Hamilton takes 28h 20m and the fastest bus takes 27h 53m. The bus runs, on average, 4 times per week from Louisville to Hamilton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

28h 20m
Duration
1,054 km
Distance
$178
Average price
4 times a week
Frequency

Louisville to Hamilton bus times

Buses run 4 times a week between Louisville and Hamilton. The service departs Louisville at 2:55 AM at night, which arrives into Hamilton at 07:43:00. All services require a transfer at Indianapolis and take an average of 28h 20m. The schedules shown below are for the next available departures.

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayBarons BusFlixbus USAGO Transit28h 48m • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayBarons BusFlixbus USAGO Transit28h 48m • 3 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayBarons BusFlixbus USAGO Transit27h 53m • 3 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayBarons BusFlixbus USAGO Transit27h 53m • 3 changes

Frequently asked questions

Want to know about travelling from Louisville to Hamilton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Louisville to Hamilton.ExpandLaunch map view
  • Distance: 1,054.1 km
  • Duration: 28h 20m

What companies run services between Louisville, KY, USA and Hamilton, ON, Canada?

You can take a bus from Louisville, KY to Main St. W. @ Summers Ln. via Indianapolis, Detroit Bus Station, Mississauga, and Square One in around 16h 24m.

Operators