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Louisville to Jacksonville buses

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Trip Overview

The average bus between Louisville and Jacksonville takes 17h 25m and the fastest bus takes 15h 20m. The bus service runs several times per day from Louisville to Jacksonville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

17h 25m
Duration
806 mi
Distance
$153
Average price
5 times a day
Frequency

Bus via Nashville

best
  1. Take the bus from Louisville Bus Station to Nashville Bus Stationbus bus
  2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
  3. Take the bus from Atlanta Bus Station to Jacksonvillebus bus
16h
$117–209

Louisville to Jacksonville bus times

Buses run 5 times a day between Louisville and Jacksonville. The earliest departure is at 1:25 AM at night, and the last departure from Louisville is at 10:55 PM which arrives into Jacksonville at 7:55 PM. All services require a transfer at Nashville Bus Station and take an average of 17h 25m. The schedules shown below are for the next available departures.

Departing Monday, October 12, 2026

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    Amtrak ThruwayGreyhound USAFlixbus USA15h 40m • 2 changes

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    Arrives next day

    Greyhound USAGreyhound USAFlixbus USA17h 5m • 2 changes

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    Arrives next day

    Flixbus USAFlixbus USAFlixbus USA15h 20m • 2 changes

Departing Tuesday, October 13, 2026

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    Flixbus USAFlixbus USAGreyhound USA18h 30m • 2 changes

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    Greyhound USAGreyhound USAGreyhound USA18h 35m • 2 changes

  •  → 

    Amtrak ThruwayGreyhound USAFlixbus USA15h 40m • 2 changes

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAFlixbus USA17h 5m • 2 changes
  • Show more

Departing Wednesday, October 14, 2026

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    Greyhound USAGreyhound USAGreyhound USA18h 35m • 2 changes

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAFlixbus USA17h 5m • 2 changes

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAFlixbus USA15h 20m • 2 changes

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    Arrives next day

    Greyhound USAGreyhound USAGreyhound USA21h • 2 changes

Departing Thursday, October 15, 2026

  •  → 

    Greyhound USAGreyhound USAGreyhound USA18h 35m • 2 changes

  •  → 

    Amtrak ThruwayGreyhound USAFlixbus USA15h 40m • 2 changes

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAFlixbus USA17h 5m • 2 changes

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAFlixbus USA15h 20m • 2 changes

Departing Friday, October 16, 2026

  •  → 

    Flixbus USAFlixbus USAGreyhound USA18h 30m • 2 changes

  •  → 

    Greyhound USAGreyhound USAGreyhound USA18h 35m • 2 changes

  •  → 

    Amtrak ThruwayGreyhound USAFlixbus USA15h 40m • 2 changes

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAFlixbus USA17h 5m • 2 changes
  • Show more

Departing Saturday, October 17, 2026

  •  → 

    Flixbus USAFlixbus USAGreyhound USA18h 30m • 2 changes

  •  → 

    Greyhound USAGreyhound USAGreyhound USA18h 35m • 2 changes

  •  → 

    Amtrak ThruwayGreyhound USAFlixbus USA15h 40m • 2 changes

  •  → 

    Arrives next day

    Greyhound USAGreyhound USAFlixbus USA17h 5m • 2 changes
  • Show more

Departing Sunday, October 18, 2026

  •  → 

    Flixbus USAFlixbus USAGreyhound USA18h 30m • 2 changes

  •  → 

    Greyhound USAGreyhound USAGreyhound USA18h 35m • 2 changes

  •  → 

    Amtrak ThruwayGreyhound USAFlixbus USA15h 40m • 2 changes

Frequently asked questions

Want to know about travelling from Louisville to Jacksonville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Louisville to Jacksonville.ExpandLaunch map view
  • Distance: 805.6 mi
  • Duration: 17h 25m

What companies run services between Louisville, KY, USA and Jacksonville, FL, USA?

You can take a bus from Louisville Bus Station to Jacksonville via Nashville Bus Station and Atlanta Bus Station in around 16h.

Operators