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Louisville to Minneapolis buses

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Trip Overview

The average bus between Louisville and Minneapolis takes 17h 13m and the fastest bus takes 16h 20m. The bus service runs several times per day from Louisville to Minneapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

17h 13m
Duration
728 mi
Distance
$150
Average price
Twice daily
Frequency

Louisville to Minneapolis bus times

Buses run twice daily between Louisville and Minneapolis. The earliest departure is at 2:55 AM at night, and the last departure from Louisville is at 8:00 AM which arrives into Minneapolis at 12:15 AM. All services require a transfer at Chicago Union Station and take an average of 17h 13m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

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    Arrives next day

    Amtrak ThruwayGreyhound USA17h 15m • 1 change

Departing Friday, November 6, 2026

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    Amtrak ThruwayFlixbus USA16h 20m • 1 change
  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USA17h 15m • 1 change

Departing Saturday, November 7, 2026

  •  → 

    Amtrak ThruwayFlixbus USA16h 20m • 1 change
  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USA17h 15m • 1 change

Departing Sunday, November 8, 2026

  •  → 

    Amtrak ThruwayFlixbus USA16h 20m • 1 change
  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USA17h 15m • 1 change

Departing Monday, November 9, 2026

  •  → 

    Amtrak ThruwayFlixbus USA16h 20m • 1 change
  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USA17h 15m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    Amtrak ThruwayFlixbus USA16h 20m • 1 change
  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USA17h 15m • 1 change

Departing Wednesday, November 11, 2026

  •  → 

    Amtrak ThruwayFlixbus USA16h 20m • 1 change
  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USA17h 15m • 1 change

Frequently asked questions

Want to know about travelling from Louisville to Minneapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Louisville to Minneapolis.ExpandLaunch map view
  • Distance: 728.1 mi
  • Duration: 17h 13m

What companies run services between Louisville, KY, USA and Minneapolis, MN, USA?

You can take a bus from Louisville, KY to Minneapolis Bus Station via Chicago Union Station and Chicago Bus Station in around 15h 29m.

Operators