Rome2Rio

Louisville to Myrtle Beach buses

Find Transport to Myrtle Beach

View schedule

Trip Overview

The bus between Louisville and Myrtle Beach takes 21h 20m. There is at least one bus per day from Louisville to Myrtle Beach. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 20m
Duration
788 mi
Distance
$172
Average price
Once daily
Frequency

Louisville to Myrtle Beach bus times

Buses run once daily between Louisville and Myrtle Beach. The service departs Louisville at 6:30 PM in the evening, which arrives into Myrtle Beach at 15:50:00. All services require a transfer at Nashville Bus Station and take an average of 21h 20m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAGreyhound USA21h 20m • 2 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAGreyhound USA21h 20m • 2 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAGreyhound USA21h 20m • 2 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAGreyhound USA21h 20m • 2 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAGreyhound USA21h 20m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAGreyhound USA21h 20m • 2 changes

Frequently asked questions

Want to know about travelling from Louisville to Myrtle Beach? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Louisville to Myrtle Beach.ExpandLaunch map view
  • Distance: 788 mi
  • Duration: 21h 20m

What companies run services between Louisville, KY, USA and Myrtle Beach, SC, USA?

You can take a bus from Louisville, KY to Myrtle Beach Bus Station via Nashville Bus Station and Atlanta Bus Station in around 17h 43m.

Operators