Rome2Rio

Louisville to North Charleston buses

Find Transport to North Charleston

View schedule
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

Trip Overview

The bus between Louisville and North Charleston takes 24h. There is at least one bus per day from Louisville to North Charleston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

24h
Duration
887 mi
Distance
$192
Average price
Once daily
Frequency

Louisville to North Charleston bus times

Buses run once daily between Louisville and North Charleston. The service departs Louisville at 6:30 PM in the evening, which arrives into North Charleston at 18:30:00. All services require a transfer at Nashville Bus Station and take an average of 24h. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAGreyhound USA24h • 2 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAGreyhound USA24h • 2 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAGreyhound USA24h • 2 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAGreyhound USA24h • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAGreyhound USA24h • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAGreyhound USA24h • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Amtrak ThruwayFlixbus USAGreyhound USA24h • 2 changes

Frequently asked questions

Want to know about travelling from Louisville to North Charleston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Louisville to North Charleston.ExpandLaunch map view
  • Distance: 886.6 mi
  • Duration: 24h

What companies run services between Louisville, KY, USA and North Charleston, SC, USA?

You can take a bus from Louisville, KY to Charleston Bus Station via Nashville Bus Station and Atlanta Bus Station in around 20h 45m.

Operators