The average bus between Louisville and Orlando Health/Amtrak takes 23h 40m and the fastest bus takes 22h 37m. The bus service runs several times per day from Louisville to Orlando Health/Amtrak. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Louisville and Orlando Health/Amtrak. The earliest departure is at 6:00 AM in the morning, and the last departure from Louisville is at 6:20 PM which arrives into Orlando Health/Amtrak at 5:29 PM. All services require a transfer at Nashville Bus Station and take an average of 23h 40m. The schedules shown below are for the next available departures.
Arrives next day




24h 58m • 4 changes
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23h 9m • 4 changes
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23h 57m • 4 changes
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23h 9m • 4 changes
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24h 56m • 4 changes
Arrives next day




23h 38m • 4 changes
Want to know about travelling from Louisville to Orlando Health/Amtrak? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Louisville to Orlando Health/Amtrak. However, there are services departing from Louisville station and arriving at Orlando Health/Amtrak station via Nashville. The journey, including transfers, takes approximately 23h 40m.
Louisville to Orlando Health/Amtrak bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
Louisville to Orlando Health/Amtrak bus services, operated by Amtrak Thruway, arrive at Orlando Bus Station.
The distance between Louisville and Orlando Health/Amtrak is 1,155.1 km. The road distance is 1,392 km.
You can take a bus from Louisville, KY to Sligh Blvd & W Copeland Dr via Nashville Bus Station, Atlanta Bus Station, Orlando Bus Station, John Young Pkwy & Amelia St, and N Garland Ave & W Amelia St in around 18h 26m.