The average bus between Louisville and Salisbury takes 30h 7m and the fastest bus takes 29h 25m. The bus service runs several times per day from Louisville to Salisbury. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Louisville and Salisbury. The earliest departure is at 7:50 AM in the morning, and the last departure from Louisville is at 3:15 PM which arrives into Salisbury at 8:40 PM. All services require a transfer at Columbus - Downtown - Mound St and take an average of 30h 7m. The schedules shown below are for the next available departures.
Arrives next day




30h 50m • 4 changes
Arrives next day




29h 25m • 4 changes
Arrives next day




30h 50m • 4 changes
Arrives next day




29h 25m • 4 changes
Arrives next day




30h 50m • 4 changes
Arrives next day




29h 25m • 4 changes
Want to know about travelling from Louisville to Salisbury? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Louisville to Salisbury. However, there are services departing from Louisville station and arriving at Salisbury station via Columbus - Downtown - Mound St. The journey, including transfers, takes approximately 30h 7m.
Louisville to Salisbury bus services, operated by Barons Bus, depart from Louisville, KY Bus Station.
Louisville to Salisbury bus services, operated by Barons Bus, arrive at Salisbury, MD station.
Book your Louisville to Salisbury bus tickets online with Barons Bus, COTA and 3 other operators.
The distance between Louisville and Salisbury is 886.1 km. The road distance is 1,271 km.
You can take a bus from Louisville, KY Bus Station to Salisbury, MD via Columbus - Downtown - Mound St, S Grant Ave & E Mound St, S High St & E Rich St, Columbus, Pittsburgh Intermodal Station, Baltimore Downtown Bus Station, and Baltimore, MD - Greyhound Bus Terminal Downtown in around 19h 24m.