The bus between Louisville and St. Louis takes 8h 25m. There is at least one bus per day from Louisville to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Louisville and St. Louis. The earliest departure is at 8:30 AM in the morning, and the last departure from Louisville is at 8:30 AM which arrives into St. Louis at 3:55 PM. All services require a transfer, and take on average 8h 25m. The schedules shown below are for the next available departures.
Want to know about travelling from Louisville to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Louisville to St. Louis. However, there are services departing from Louisville station and arriving at St. Louis station via Evansville, IN. The journey, including transfers, takes approximately 8h 25m.
Louisville to St. Louis bus services, operated by Miller Transportation, depart from Louisville, KY station.
Louisville to St. Louis bus services, operated by Miller Transportation, arrive at St Louis Bus Station.
Book your Louisville to St. Louis bus tickets online with Miller Transportation and Greyhound USA.
The distance between Louisville and St. Louis is 388.7 km. The road distance is 461 km.
You can take a bus from Louisville, KY to St Louis Bus Station via Evansville Bus Station in around 6h 40m.
