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Louisville to Tuscaloosa buses

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Trip Overview

The average bus between Louisville and Tuscaloosa takes 16h 13m and the fastest bus takes 15h 30m. The bus service runs several times per day from Louisville to Tuscaloosa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

16h 13m
Duration
621 mi
Distance
$137
Average price
Twice daily
Frequency

Louisville to Tuscaloosa bus times

Buses run twice daily between Louisville and Tuscaloosa. The earliest departure is at 7:25 AM in the morning, and the last departure from Louisville is at 6:30 PM which arrives into Tuscaloosa at 9:00 AM. All services require a transfer at Nashville Bus Station and take an average of 16h 13m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

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    Amtrak ThruwayGreyhound USAGreyhound USA17h 5m • 2 changes
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    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USA15h 30m • 2 changes

Departing Tuesday, November 3, 2026

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    Amtrak ThruwayGreyhound USAGreyhound USA17h 5m • 2 changes
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    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USA15h 30m • 2 changes

Departing Wednesday, November 4, 2026

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    Amtrak ThruwayGreyhound USAGreyhound USA17h 5m • 2 changes
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    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USA15h 30m • 2 changes

Departing Thursday, November 5, 2026

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    Amtrak ThruwayGreyhound USAGreyhound USA17h 5m • 2 changes
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    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USA15h 30m • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Amtrak ThruwayGreyhound USAGreyhound USA17h 5m • 2 changes
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    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USA15h 30m • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Amtrak ThruwayGreyhound USAGreyhound USA17h 5m • 2 changes
  •  → 

    Arrives next day

    Amtrak ThruwayGreyhound USAGreyhound USA15h 30m • 2 changes

Frequently asked questions

Want to know about travelling from Louisville to Tuscaloosa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Louisville to Tuscaloosa.ExpandLaunch map view
  • Distance: 621.1 mi
  • Duration: 16h 13m

What companies run services between Louisville, KY, USA and Tuscaloosa, AL, USA?

You can take a bus from Louisville, KY to Tuscaloosa Bus Stop via Nashville Bus Station and Atlanta Bus Station in around 13h 25m.

Operators